ladygaga
If you have guests visiting from out of town,
La Esquina- Killer margaritas, good Mexican food, great music. People always seem to have a good time here- you'll be eating in a cave-like ambiance.
Freemans Alley- Great hipster chic ambiance, excellent food (esp. meats and game), good people watching.
Lucky Chang's- The Chinese food is not amazing, but the live dinner entertainment (karaoke by drag queens) can be fun for bachelorette parties. Super touristy though.